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Quantum Chemistry
Deuterium and its role in the machinery of evolution.
PubMed
Authors: Pedersen LG, Bartolotti L, Li L
Year
2006
Paper ID
12807
Status
Peer-reviewed
Abstract Read
~2 min
Abstract Words
67
Citations
N/A
Abstract
An argument is presented that the spontaneous mutation rate, the core of evolution theory, may be dictated by the deuterium/hydrogen (D/H) abundance ratio. This argument is supported by quantum mechanical calculations of the zero-point energy reduction for DNA base pairs upon deuterium substitution for hydrogen and recent experiments that show that the rate of catalytic dsDNA unwinding is dependent on the stability of the dsDNA.
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- An argument is presented that the spontaneous mutation rate, the core of evolution theory, may be dictated by the deuterium/hydrogen (D/H) abundance ratio.
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