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CdSe quantum dots as luminescent probes for spironolactone determination.

PubMed
Authors: Liang J, Huang S, Zeng D, He Z, Ji X, Ai X, Yang H

Year

2006

Paper ID

12788

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

93

Citations

131

Abstract

Based on the quenching of the fluorescence of CdSe quantum dots (QDs) by spironolactone, a simple, rapid and specific method for spironolactone determination was proposed. In the optimum conditions, spironolactone concentration versus quantum dot fluorescence gave a linear response with an excellent 0.997 correlation coefficient, between 2.5 and 700 mg/mL (6.0-1680 micromol/L) and the limit of detection S/N=3 was 0.2 microg/mL (0.48 micromol/L). The contents of spironolactone in pharmaceutical tablets were determined by the proposed method and the results agreed with the claimed values. The possible mechanism for the reaction was also discussed.

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  • This paper contributes to the Quantum Chemistry research area in the Quantum Articles archive.
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  • Based on the quenching of the fluorescence of CdSe quantum dots (QDs) by spironolactone, a simple, rapid and specific method for spironolactone determination was proposed.

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References & Citation Signals

[1] DOI https://doi.org/10.1016/j.talanta.2005.09.004 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/18970543/

Local Citation Graph (Related-Paper Links)

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External citation index: OpenAlex citation signal • updated 2026-06-19 15:47:44

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