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Study on DNA damage induced by CdSe quantum dots using nucleic acid molecular "light switches" as probe.

PubMed
Authors: Liang J, He Z, Zhang S, Huang S, Ai X, Yang H, Han H

Year

2007

Paper ID

12722

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

89

Citations

62

Abstract

The calf thymus DNA (ctDNA) damage induced by water-soluble CdSe quantum dots (QDs) was investigated using nucleic acid molecular "light switches" as probe. It was found that little ctDNA was damaged by CdSe QDs without UV irradiation. However, under UV irradiation, ctDNA was nicked by CdSe QDs very clearly. The mechanism of ctDNA damage was also discussed. The results strongly suggested that the ctDNA damage caused by CdSe QDs was not due to photo-induced liberation of Cd(2+), but due to the production of free radicals and reactive oxygen species.

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  • This paper contributes to the Quantum Chemistry research area in the Quantum Articles archive.
  • It adds a 2007 reference point for readers tracking recent quantum research.
  • The calf thymus DNA (ctDNA) damage induced by water-soluble CdSe quantum dots (QDs) was investigated using nucleic acid molecular "light switches" as probe.

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References & Citation Signals

[1] DOI https://doi.org/10.1016/j.talanta.2006.07.048 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/19071507/

Local Citation Graph (Related-Paper Links)

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External citation index: OpenAlex citation signal • updated 2026-06-17 00:39:50

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