Quick Navigation

Overview Topics Abstract Importance Paper Tools References Reactions Discussion Publication

Topics

Quantum Error Correction Fault Tolerance Quantum Optimization Quantum Device Fabrication Process Engineering Qubit Coherence Noise Stability Characterization

Synthesis of Fused sp(3)-Enriched Imidazoles.

PubMed
Authors: Lysenko V, Portiankin A, Shvydenko T, Shishkina S, Nazarenko K, Kostyuk A

Year

2025

Paper ID

9569

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

100

Citations

0

Abstract

A synthetic approach to imidazoles annulated to saturated six-membered cycles featuring S, SO, NH, NCbz was developed. It was achieved by combining the Neber rearrangement and the Marckwald reaction. The Neber rearrangement applied to cyclic ketones allowed us to prepare in hundred gram quantities previously unknown α-amino ketones. Unstable tosyl ketoximes were used without purification immediately after their preparation. α-Amino ketones react with potassium thiocyanate and cyanate in almost a quantitative yield affording highly pure imidazol-2-thiones or imidazol-2-ones. Desulfurization of imidazole-2-thiones using Raney nickel led to the formation of previously unknown 2-unsubstituted fused imidazoles in high yields.

Why This Paper Matters

  • This paper contributes to the Quantum Error Correction & Fault Tolerance research area in the Quantum Articles archive.
  • It adds a 2025 reference point for readers tracking recent quantum research.
  • A synthetic approach to imidazoles annulated to saturated six-membered cycles featuring S, SO, NH, NCbz was developed.

Paper Tools

Become a member to use research tools

Sign in to open papers, visit source links, share, cite, compare, copy DOI links, request category corrections, and build your reading list.

Become a member Sign in
Publisher Share Cite This Paper Copy URL Compare Copy DOI Add to Reading List Category Correction Request

References & Citation Signals

[1] DOI https://doi.org/10.1002/open.202400272 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/39538972/

Local Citation Graph (Related-Paper Links)

Current Paper #9569

External citation index: OpenAlex citation signal • updated 2026-10-31 23:44:39

Community Reactions

Quick sentiment from readers on this paper.

Score: 0
Likes: 0 Dislikes: 0

Sign in to react to this paper.

Discussion & Reviews (Moderated)

Average Rating: 0.0 / 5 (0 ratings)

No written reviews yet.