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Quantum State Preparation Representation

Indole diketopiperazine alkaloids from the deep-sea-derived fungus Aspergillus sp. FS445.

PubMed
Authors: Liu Z, Chen Y, Li S, Hu C, Liu H, Zhang W

Year

2022

Paper ID

895

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

99

Citations

23

Abstract

Twelve indole diketopiperazine alkaloids (‒) including four new ones aspechinulins A‒D (, , and ) were isolated from the deep-sea-derived fungus sp. FS445. Their structures were elucidated through spectroscopic analysis and the absolute configurations were determined by analyzing the experimental ECD data as well as the quantum chemical calculations. Compounds , and represented the first examples of indole diketopiperazine derivatives constructing a C unit at 11-NH through an imide linkage. The NO production inhibitory activity of the isolated compounds was evaluated and compounds ‒, and exhibited potential inhibitory activities against NO production with the IC values in the range of 20 ∼ 90 µM.[Formula: see text].

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  • This paper contributes to the Quantum State Preparation & Representation research area in the Quantum Articles archive.
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  • Twelve indole diketopiperazine alkaloids (‒) including four new ones aspechinulins A‒D (, , and ) were isolated from the deep-sea-derived fungus sp.

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References & Citation Signals

[1] DOI https://doi.org/10.1080/14786419.2021.1925271 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/33977842/

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