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Quantum Control Electronics System Integration

Sesquiterpenoids from Ixeris sonchifolia and their neuroprotective activities.

PubMed
Authors: Yuan Y, Hu ZF, Wang FL, Wan LS, Gong Y, Chen JC

Year

2022

Paper ID

880

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

81

Citations

2

Abstract

The phytochemical investigation of the methanol extract of led to the isolation and identification of nine analogs, including one new guaiane-type sesquiterpenoid, named ixerinoid A (). The structure of was determined by extensive analysis of the 1 D and 2 D nuclear magnetic resonance spectroscopic data, as well as quantum chemical calculations. Additionally, all the isolates were tested for their neuroprotective activity using the oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cell injury model. Compounds , , , , and displayed remarkable protective effects at concentrations of 1, 5, and 10 M, respectively.

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  • The phytochemical investigation of the methanol extract of led to the isolation and identification of nine analogs, including one new guaiane-type sesquiterpenoid, named...

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References & Citation Signals

[1] DOI https://doi.org/10.1080/10286020.2021.2017896 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/34951327/

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