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New cytochalasans from an endophytic Xylaria species associated with Costa Rican Palicourea elata (Rubiaceae).

PubMed
Authors: Hinterdobler W, Bacher M, Shi BB, Baurecht D, Krisai-Greilhuber I, Schmoll M, Brecker L, Valant-Vetschera K, Schinnerl J

Year

2023

Paper ID

873

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

85

Citations

4

Abstract

Four new leucine-derived cytochalasans, possessing a 5,6,5,8-ring () and a 5,6,11-ring core (-), were isolated from a cultivated endophytic fungus sp. strain WH2D4 (Xylariaceae). This fungus was isolated from leaves of the neotropical tree species (Sw.) Borhidi (Rubiaceae) collected in Costa Rica. The chemical structures were determined by employing IR, MS as well as 1D- and 2D-NMR experiments. The stereochemistry at C-15 of compound was determined by quantum calculations. The isolated compounds did not affect germination and growth of and the opportunistic human fungal pathogen .

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  • This paper contributes to the Quantum State Preparation & Representation research area in the Quantum Articles archive.
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  • Four new leucine-derived cytochalasans, possessing a 5,6,5,8-ring () and a 5,6,11-ring core (-), were isolated from a cultivated endophytic fungus sp.

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