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Sono-Maceration - a rapid and inexpensive method for the isolation of ursolic acid from Neolamarckia cadamba leaves.

PubMed
Authors: George J, Meshram GA, Patil VR

Year

2023

Paper ID

866

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

111

Citations

N/A

Abstract

This article records for the first time the isolation of Ursolic acid from the leaves of (Roxb.) Bosser (Family: Rubiaceae) using ultrasonic waves. This bioactive triterpenic acid was isolated without its isomer, oleanolic acid, in a very convenient way with good yield. The structure was identified by means of one dimensional Nuclear Magnetic Resonance (NMR) spectroscopic techniques like H NMR, C NMR, distortionless enhancement by polarization transfer (DEPT) and two dimensional NMR spectroscopic method for example, heteronuclear single quantum coherence (HSQC). It was also assayed for antidiabetic and antioxidant potencies. About 71.5 mg of pure ursolic acid was isolated from 2.6 grams of ethyl acetate soluble fraction using sono-maceration as an extraction technique.

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  • This paper contributes to the Quantum Device Fabrication & Process Engineering research area in the Quantum Articles archive.
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  • This article records for the first time the isolation of Ursolic acid from the leaves of (Roxb.) Bosser (Family: Rubiaceae) using ultrasonic waves.

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