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Quantum State Preparation Representation

Bixasteroid, a new compound from the fruits of Bixa orellana and its anti-inflammatory activity.

PubMed
Authors: Chen YM, Xu TQ, Zhang XQ, Fan CL, Ye WC, Xu W, Zhou GX

Year

2023

Paper ID

865

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

97

Citations

5

Abstract

Bixasteroid (), one new steroid together with five known compounds (-), were isolated from the ethyl acetate fraction of ethanol extract of fruits. All of these known compounds were isolated from the plant for the first time. Their structures were elucidated on the basis of spectroscopic analysis, and the absolute configuration of compound was determined by X-ray crystallographic data analysis as well as by the quantum chemical ECD calculations. All the isolated compounds were tested for their anti-inflammatory activities. Compounds and showed inhibiting NO release activities in LPS-induced RAW 264.7 macrophages with the IC values of 4.72 ± 0.28 and 5.48 ± 1.48 M, respectively.

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  • Bixasteroid (), one new steroid together with five known compounds (-), were isolated from the ethyl acetate fraction of ethanol extract of fruits.

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References & Citation Signals

[1] DOI https://doi.org/10.1080/14786419.2021.1974436 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/34507510/

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