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Two new monoterpenoid indole alkaloids from the kernels of Kopsia arborea.

PubMed
Authors: Chen C, Ding X, Han L, Zhu W, Huang K, Hao X, Zhang Y

Year

2023

Paper ID

858

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

53

Citations

N/A

Abstract

Two new monoterpenoid indole alkaloids, (2 , 7 , 16 , 20 , 21)-12-hydroxypleiocarpine () and (2, 7 , 16, 20 , 21)--methoxycarbonyl-11,12-methylenedioxy-Δ-kopsinaline (), along with six known alkaloids were isolated from the methanol extract of the kernels of . Their structures including the absolute configurations were elucidated by HRESIMS, NMR spectroscopy, and quantum computational methods. Their cytotoxicity against two human cancer cell lines were also evaluated.

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  • Two new monoterpenoid indole alkaloids, (2 , 7 , 16 , 20 , 21)-12-hydroxypleiocarpine () and (2, 7 , 16, 20 , 21)--methoxycarbonyl-11,12-methylenedioxy-Δ-kopsinaline (), along...

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