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Quantum State Preparation Representation

Herpetosin A, a nor-cucurbitane triterpenoid with a 5/6/6/5 ring system from Herpetospermum pedunculosum.

PubMed
Authors: Chen Q, Ma Y, Dong Z, Xu B, Wang G, Lan X, Liao Z, Chen M

Year

2026

Paper ID

835

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

78

Citations

0

Abstract

Two previously undescribed triterpenoids, herpetosin A () and herpetosin B (), together with two known compounds, cucurbitacin B () and dihydrocucurbitacin E (), were isolated from the seeds of Their structures were elucidated by analysis of the NMR, HR-ESI-MS, X-ray data and quantum chemical calculation. Compound featured an unprecedented nor-cucurbitane triterpenoid skeleton with a 5/6/6/5 ring system. Among all the isolates, compound exhibited anti-proliferative effect with IC values of 4.5 ± 0.1 M against A549 cells, 8.2 ± 0.5 M against MDA-MB-231 cells, and 2.4 ± 0.3 M against HepG2 cells, respectively.

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  • This paper contributes to the Quantum State Preparation & Representation research area in the Quantum Articles archive.
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  • Two previously undescribed triterpenoids, herpetosin A () and herpetosin B (), together with two known compounds, cucurbitacin B () and dihydrocucurbitacin E (), were isolated...

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References & Citation Signals

[1] DOI https://doi.org/10.1080/14786419.2024.2424399 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/39497678/

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