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Inhibition of Mincle signaling by chemically synthesized disaccharide-type 6-O-acylated steryl β-glucosides (βASGs) and their analogues derived from plants.
PubMed
Authors: Yoshida K, Matsumaru T, Yamasaki S, Fujimoto Y
Year
2026
Paper ID
72077
Status
Peer-reviewed
Abstract Read
~2 min
Abstract Words
42
Citations
N/A
Abstract
Chemically synthesized disaccharide βASGs from and analogues effectively block Mincle-mediated signaling. This Mincle signaling inhibition requires a disaccharide backbone with sterol and fatty acid moieties, suggesting these glycolipids as key structural templates for developing novel anti-inflammatory therapeutics targeting this C-type lectin receptor.
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- It adds a 2026 reference point for readers tracking recent quantum research.
- Chemically synthesized disaccharide βASGs from and analogues effectively block Mincle-mediated signaling.
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