Hierarchical Progressive Pauli Noise Modeling with Residual Compensation for Multi-Qubit Quantum Circuits

Quantum Noise Characterization (QNC) is indispensable for benchmarking and mitigating errors in Noisy Intermediate-Scale Quantum (NISQ) devices. However, traditional Quantum Process Tomography (QPT) suffers from an exponential parameter explosion O\(4^N\), severely hindering its scalability. In this paper, we propose a Hierarchical Progressive Optimization (HPO) framework to efficiently extract high-order spatial crosstalk in multi-qubit systems. By introducing a mathematically rigorous combinatorial projection mask, the HPO framework strategically freezes foundational low-weight topologies and exclusively isolates high-weight Pauli correlations. This progressive masking mechanism effectively reduces the optimization complexity from O\(4^N\) to a scalable O\(N cdot 4^w\), successfully mitigating the barren plateau phenomenon. Simulations show that our method achieves a remarkable parameter compression rate of 96.3% on a 5-qubit system while maintaining machine precision convergence. Furthermore, to validate its practical utility, we apply the extracted spatial crosstalk model to perform Quantum Error Mitigation (QEM) on a deep-circuit 10-qubit Harrow-Hassidim-Lloyd (HHL) algorithm. Compared to the traditional global depolarizing baseline, the HPO-guided mitigation scheme breaks the unmitigated crosstalk bottleneck, achieving an unprecedented state fidelity recovery from 0.7431 to 0.9381 $ΔF approx 19.5\%$. Our work provides a scalable, highly accurate, and indispensable blueprint for modeling and mitigating complex multi-body errors in large-scale quantum algorithms.