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Qubit Coherence Noise Stability Characterization

A novel label free electrochemiluminescent aptasensor for the detection of lysozyme.

PubMed
Authors: Khonsari YN, Sun S

Year

2019

Paper ID

1734

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

112

Citations

22

Abstract

In this paper we describe a novel ultrasensitive electrochemiluminescent (ECL) aptasensor based on the quenching effect of aptamer and lysozyme incubation on co-reactant ECL mechanism of nitrogen-doped graphene quantum dots and persulfate. Incorporation of gold nanoparticles let to enhancement of electron transfer process of co-reactant mechanism species. The electrochemical behavior of each step modification of aptasensor was investigated using electrochemical impedance spectroscopy and verified by ECL responses. The aptasensor showed high stability, sensitivity, reliable reproducibility, wide linear range (10 fM to 10 nM) with a low detection limit of 0.8 fM at an S/N ratio of 3, n = 10 can be successively applied to the human serum samples analysis. Recoveries ranged between 91 and 104% (with RSDs of <3.1%).

Why This Paper Matters

  • This paper contributes to the Qubit Coherence, Noise & Stability Characterization research area in the Quantum Articles archive.
  • It adds a 2019 reference point for readers tracking recent quantum research.
  • In this paper we describe a novel ultrasensitive electrochemiluminescent (ECL) aptasensor based on the quenching effect of aptamer and lysozyme incubation on co-reactant ECL...

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References & Citation Signals

[1] DOI https://doi.org/10.1016/j.msec.2018.11.016 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/30606520/

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