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Quantum Device Fabrication Process Engineering

Isochromanes from Aspergillus fumigatus, an endophytic fungus from Cordyceps sinensis.

PubMed
Authors: Li XH, Han XH, Qin LL, He JL, Cao ZX, Gu YC, Guo DL, Deng Y

Year

2019

Paper ID

1527

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

87

Citations

N/A

Abstract

Four previously undescribed isochromanes were isolated from the fermentation broth of an endophytic fungus , which was obtained from the fruiting body of . Their structures were elucidated through extensive spectroscopic analyses. One racemic isochromane was further purified by chiral HPLC to yield a pair of enantiomers and their absolute configurations were determined by quantum chemical ECD calculations. These isolated compounds were evaluated for cytotoxicity against two cell lines (MV4-11 and MDA-ME-231) and the result showed that compounds and exhibited moderate growth inhibition against MV4-11 cell line.

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  • This paper contributes to the Quantum Device Fabrication & Process Engineering research area in the Quantum Articles archive.
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  • Four previously undescribed isochromanes were isolated from the fermentation broth of an endophytic fungus , which was obtained from the fruiting body of .

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References & Citation Signals

[1] DOI https://doi.org/10.1080/14786419.2018.1478824 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/29792356/

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