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Quantum State Preparation Representation

Sesquiterpenoids from the roots of Croton crassifolius.

PubMed
Authors: Tian JL, Li CX, Shang XY, Hou XW, Zhang Y, Li LZ, Huang XX, Song SJ

Year

2019

Paper ID

1525

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

84

Citations

10

Abstract

Phytochemical investigation of roots afforded five sesquiterpenes (), including two new sesquiterpenes 6-hydroxy-cyperenoic acid () and crassifterpenoid A (), together with three known compounds (). The structures of the new compounds were determined by comprehensive spectroscopic methods, and their absolute configurations were determined by quantum chemical ECD calculation. Crassifterpenoid A () is the first germacrane-type sesquiterpene isolated from , which enriched the diversity of chemical constituents in . In addition, the cytotoxicities of all compounds against human liver cancer lines HepG2 and Hep3B were determined, but none showed significant activity.

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  • Phytochemical investigation of roots afforded five sesquiterpenes (), including two new sesquiterpenes 6-hydroxy-cyperenoic acid () and crassifterpenoid A (), together with...

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