Quick Navigation

Overview Topics Abstract Importance Paper Tools References Reactions Discussion Publication Related

Topics

Quantum Chemistry Spin Qubits Silicon Quantum Computing

High-resolution NMR of encapsulated proteins dissolved in low-viscosity fluids.

PubMed
Authors: Wand AJ, Ehrhardt MR, Flynn PF

Year

1998

Paper ID

13431

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

90

Citations

122

Abstract

The majority of known proteins are too large to be comprehensively examined by solution NMR methods, primarily because they tumble too slowly in solution. Here we introduce an approach to making the NMR relaxation properties of large proteins amenable to modern solution NMR techniques. The encapsulation of a protein in a reverse micelle dissolved in a low-viscosity fluid allows it to tumble as fast as a much smaller protein. The approach is demonstrated and validated with the protein ubiquitin encapsulated in reverse micelles prepared in a variety of alkane solvents.

Why This Paper Matters

  • This paper contributes to the Quantum Chemistry research area in the Quantum Articles archive.
  • It adds a 1998 reference point for readers tracking recent quantum research.
  • The majority of known proteins are too large to be comprehensively examined by solution NMR methods, primarily because they tumble too slowly in solution.

Paper Tools

Become a member to use research tools

Sign in to open papers, visit source links, share, cite, compare, copy DOI links, request category corrections, and build your reading list.

Become a member Sign in
Publisher Share Cite This Paper Copy URL Compare Copy DOI Add to Reading List Category Correction Request

References & Citation Signals

[1] DOI https://doi.org/10.1073/pnas.95.26.15299 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/9860963/

Local Citation Graph (Related-Paper Links)

Current Paper #13431 #78837 TLS loss in superconducting res... #78797 Local polarization control of o... #78792 Demonstration of subspace-searc...

External citation index: OpenAlex citation signal • updated 2026-10-21 22:52:13

Community Reactions

Quick sentiment from readers on this paper.

Score: 0
Likes: 0 Dislikes: 0

Sign in to react to this paper.

Discussion & Reviews (Moderated)

Average Rating: 0.0 / 5 (0 ratings)

No written reviews yet.