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Synthesis and fluorescence investigation of differently substituted benzo[b][1,8]naphthyridines: interaction with different solvents and bovine serum albumin (BSA).

PubMed
Authors: Shelar DP, Patil SR, Rote RV, Toche RB, Jachak MN

Year

2011

Paper ID

12343

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

78

Citations

10

Abstract

A series of benzo[b][1, 8]naphthyridines has been synthesized by Friedländer condensation of 2-aminoquinoline-3-carbaldehyde 1 (o-aminoaldehyde) with active methylenes in basic medium. The fluorescence spectroscopic properties of some representative compounds has been studied in different organic solvents; moreover interaction with bovine serum albumin (BSA) in phosphate buffer was examined by UV-vis and fluorescence spectroscopy. The effect of electron donor-acceptor substituents on fluorescence properties of benzo[b][1, 8]naphthyridines 13(a-n) has been investigated along with their fluorescent quantum yields.

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  • A series of benzo[b][1, 8]naphthyridines has been synthesized by Friedländer condensation of 2-aminoquinoline-3-carbaldehyde 1 (o-aminoaldehyde) with active methylenes in basic...

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References & Citation Signals

[1] DOI https://doi.org/10.1007/s10895-010-0783-1 [2] Publisher https://pubmed.ncbi.nlm.nih.gov/21152962/

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