Climate friendly MOFs synthesis for drug delivery systems by integrating AI, intelligent manufacturing, and quantum solutions in industry 6.0 sustainable approach

Abstract Since the Industrial Revolution, ecological damage, ecosystem disruption, and climate change acceleration have frequently resulted from human advancement at the price of the environment. Due to the rise in illnesses, Industry 6.0 calls for a renewed dedication to sustainability with latest technologies. Focused research and creative solutions are needed to achieve the UN Sustainable Development Goals (SDGs), especially 3, 9, 13, 14, 15, 17. A promising sustainable technology for enhancing healthcare while reducing environmental effect is Metal Organic Frameworks (MOFs). MOFs are perfect for drug administration because of their high surface areas, adjustable pore sizes, and remarkable drug-loading capacities. They are created by combining advanced artificial intelligence, intelligent manufacturing, and quantum computing. Researchers can create MOFs with functional groups or ligands that bind selectively to target cells or tissues, minimizing off-target effects, thanks to the distinct benefits that families like MIL, HKUST, UiO, and ZIF etc. offer for targeted drug delivery. Combining MOFs with other nanomaterials results in multipurpose systems that can handle challenging biomedical issues. Despite its promise, there are still issues with MOFs’ possible toxicity and long-term stability in physiological settings. To advance their medicinal applications, these problems must be resolved. Researchers can increase the usefulness of MOFs in medicine by critically analysing these limitations and putting up creative alternatives. The creation of MOFs especially with advanced technologies (additive manufacturing etc.) for drug delivery is a prime example of how scientific advancement and environmental stewardship may coexist to provide healthcare solutions that are advantageous to both people and the environment.