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Two new furanone derivatives from the endophytic fungus Byssochlamys sp. and their cytotoxic activities.

PubMed
Authors: Wang J, Gao WB, Liu FW, Liu Q, Song B, Ye J, Chen Y, Zhao CL, Dong W, Guo LN, Song B

Year

2024

Paper ID

1001

Status

Peer-reviewed

Abstract Read

~2 min

Abstract Words

93

Citations

2

Abstract

Two new furanone derivatives, byssochlanones A-B (-) were purified from the endophytic fungus sp. isolated from the wetland plant, . Their structures were elucidated on the basis of extensive spectroscopic analyses. Compounds - represented typical furanone analogues which are not common in natural products. The absolute configuration of compounds - were identified through quantum-chemical electronic circular dichroism (ECD) calculation compared with their experimental CD. In addition, compounds - were tested for their cytotoxic activities against HCT-8 and Hela cancer cell lines, and compound showed moderate activity against HCT-8 cells with IC value of 21.3 M.

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  • This paper contributes to the Quantum State Preparation & Representation research area in the Quantum Articles archive.
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  • Two new furanone derivatives, byssochlanones A-B (-) were purified from the endophytic fungus sp.

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